Investigating the role of IGFBP-5 in hypertension related fibrosis
Fibrosis occurs as a consequence of the increased deposition of components of the extracellular matrix (e.g. collagen) in a tissue/organ leading to increased tissue rigidity.
Research Opportunities
Summary
Furthermore, fibrosis is associated with hypertensive disorders and manifests as cardiac (heart) fibrosis in systemic hypertension (raised arterial blood pressure) and pulmonary (lung) fibrosis in pulmonary arterial hypertension (PAH) leading to decreased compliance and impaired function of both organs. The expression of insulin-like growth factor binding protein-5 (IGFBP-5) is increased in the lungs of patients with idiopathic pulmonary fibrosis, however its role in this condition is unknown. Limited in vitro studies have also suggested IGFBP-5 may possess pro-fibrotic effects however its role in hypertension-related fibrotic disease has yet to be fully explored. The proposed PhD project will therefore examine the potential role of IGFBP-5 in both PAH and arterial hypertension.
Supervisor
Discuss this further with the potential supervisor for this research degree:
Research Theme
Find other Research Degrees in the same theme:
About our Research Degrees
We welcome specific ideas from applicants for a potential research degree topic. The University offers a number of potential self-funded topics in each School which you could consider developing your research project around.
It is not unusual for a proposed research degree topic to evolve as you progress through the application stage and even your future studies. This ensures the best match of your academic/professional experience with that of your supervisory team.
Occasionally, the University will also advertise available funded studentships, for very specific topics or subjects:
If you need any further support prior to applying, please email researchdegrees@rgu.ac.uk
Entry requirements
Entry Requirements for Research Degrees
Normal entry requirements are a first or upper second class honours degree from a University of the United Kingdom, or from an overseas University, or degree equivalent qualification, subject to the approval of Robert Gordon University.
Applicants holding other qualifications shall be considered on their merits and in relation to the nature and scope of the proposed research programme.
Applicants will normally register for an MSc/PhD or MRes/PhD with transfer to PhD dependent on satisfactory progress. However, applicants who already possess a Master’s degree which includes a significant research component could be registered directly for a PhD, subject to a satisfactory research proposal, and clear evidence of research expertise.
Some Research Degree Topics require employment experience, research experience and/or transcripts for international qualifications.
Contact researchdegrees@rgu.ac.uk to see if you are eligible.
English Language
Any applicant whose first language or language of previous University-level instruction is not English must normally demonstrate competence in English. This should be a score of IELTS 6.5 with 6.5 in all elements, or an approved equivalent.
We accept a variety of in-country and secure English language tests, find out more:
Please note, some courses may require a higher standard of English than stated in this page. Contact researchdegrees@rgu.ac.uk for further information.
Fees & Costs
For Academic Year 2023/2024
UK/EU Students
- Full time - £4,712 per academic year
- Part time MPhil/PhD - £2,830 per academic year
- Part time MRes/MSc by research - £2,356 per academic year
International Students
- Full time - £18,700 per academic year
- Part-time MPhil/PhD - £11,220 per academic year
- Part-time MRes/MSc by research - £9,350 per academic year
Additional Costs
The following course-related costs are not included in the course fees:
- The cost of books that you may wish to purchase
- Accommodation and living costs
- Printing
Alumni Discount
Robert Gordon University is delighted to offer a 20% loyalty discount on course fees for all alumni who have graduated from RGU.
Scholarships and Financial Awards
Postgraduate research students will normally make their own arrangements for payment of fees. However you may qualify for a scholarship or financial award:
Funded Studentships
Occasionally, the University will also advertise available funded studentships, for very specific topics or subjects:
Disclaimer
For new intakes course fees are reviewed and published annually for each mode of delivery. Tuition fees are fixed for the duration of a course at the rate confirmed in the offer letter. For further information see:
How to Apply
Applications
All applications should be made via the University's online application for research students.
Before you apply, find out more about the application process, research proposal writing guides, routes and durations:
Our Research degrees usually start in February and October each year. There are no formal deadlines for you to submit your application, though we recommend you submit it as early as possible in order to ensure we can help you join us at your preferred time.
Completed application forms should be accompanied by:
- Degree certificate
- Statement of purpose, detailing why you would like to study this degree in the UK, and why you have chosen RGU.
- A short research proposal, in the range of 1,500 - 3,000 words, containing a rationale and background, study aims and objectives, a literature review, proposed research methods and a full reference list.
Further guidance on the application process:
English Language Requirements
All applicants whose first language is not from a recognised English speaking country will be asked to provide evidence of their English language skills as part of their offer to study at RGU.
Find out more about the English language qualification we accept:
Ready to start this Research Degree?
Find out about our entry requirements, application dates and how to apply.
Any questions?
Get in touch with our team and we'll do our best to help.